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Exosome and Secretome Research

EXOSOME RESEARCH

DEFINITION

Exosomes are extracellular vesicles that are produced by all cells and contain metabolites, proteins, lipids, and nucleic acids. They play a role in both healthy and unhealthy intercellular communication as well as numerous aspects of cell biology.

FUNCTION OF EXOSOMES

    • ​Cell metabolism and signaling
    • Tumor metastasis and immunosuppression
    • Immune activation, wound healing
    • Cell adhesion and mortility
    • Inflammation
    • Exchange of pathogenic material
    • Development and regeneration
    • Stemness and reprogramming
    • Neuronal development and homeostatsis
    • Neurodegenerative disease

SOURCES

Exosomes produced from various cell sources including

    • Fibroblasts
    • Tumor cells
    • Amniotic fluid
    • Cardiomyocytes
    • Placental tissue
    • Cardiac Precursor Cells
    • Mesenchymal Stem Cells (MSCs)
exosome-therapy-1_orig
Figure 1 Differentiation capacity of MSCs

WHAT WE OFFER?

CelltiX

EXOSOME RESEARCH - CELLTIX

CelltiX is an extracted communicating vesicle derived from Umbilical Cord-Derived Mesenchymal Stem Cells (MSCs). CelltiX is prepared in our state-of-the-art cGMP facility.

CelltiX is a new type of major paracrine factor released by MSCs into a culture medium, playing an important role in a multitude of biological processes.
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SECRETOME RESEARCH

DEFINITION

The collection of proteins that an organism secretes into the extracellular environment is known as its secretome. This portion of the human proteome contains 13–20% of all proteins, including shed receptors, extracellular matrix proteins and regulators, growth factors, and cytokines.

FUNCTION OF SECRETOME

    • Cell migration
    • Cell signaling
    • Cell communication
Figure 1 The illustration of secretome.

SOURCES

    • Skin tissue
    • Bone marrow
    • Adipose tissue
    • Neonatal tissue
    • Peripheral blood
    • Mesenchymal Stem Cells (MSCs)
Figure 2 The bioactive elements of the secretome of mesenchymal stromal cells (MSCs).

MEDICAL PRODUCTS

CelltiX

​CELLTIX

CelltiX is an extracted communicating vesicles derived from Umbilical Cord Derived Mesenchymal Stem Cells (MSCs). CelltiX is prepared in our state-of-the-art cGMP facility. Celltix is a new type of major paracrine factor released by MSCs into a culture medium playing an important function in a multitude of biological processes.
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CelltiSS

CELLTISS

CelltiSS is a conditioned media formulated for topical administration to wound areas, used to treat and manage wounds and major skin loss. CelltiSS consists of various types of bioactive factors secreted by fibroblasts. The conditioned media is obtained from a cell culture collected at 80-90% confluency of the culture, at which point the cells are in a mitotic phase, and there is maximum production of bioactive factors.
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BEAUTY PRODUCTS

celltishine_orig

CELLTISHINE PREMIUM

CelltiShine Premium contains the highest concentration of natural human growth factors, cytokines and interleukins on the market. It is designed to enhance the skin’s natural regeneration and repair process by stimulating collagen production, promoting healthy circulation, and increasing cellular renewal.
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TALK TO US

​If you feel we might be able to offer meaningful improvement to both your condition and your quality of life, then please reach out to schedule a free consultation with one of our in-house clinical experts. We offer consultations in both Malay and English. 

​During your consultation, we will: we will:

Review your medical history & recent evaluations

Explore what your treatment package might look like​

Answer any questions you have about us

Answer any questions you have about the therapies

Discuss practical next steps, ​if you feel we can effectively treat you

To schedule your consultation, click the button below

Book Now >

Review your medical history & recent evaluations

Explore what your treatment package might look like​

Answer any questions you have about us

Answer any questions you have about the therapies

Discuss practical next steps,
​if you feel we can effectively treat you

CELL TISSUE TECHNOLOGY SDN BHD

Malaysia's FIRST Tissue Engineering Firm

Established in 2010, Cell Tissue is a Malaysian advanced medical technologybased company, a spin-off of the National University of Malaysia (UKM), one of the country’s leading universities and research institutes.

Cell Tissue is known as Malaysia’s FIRST Tissue Engineering Firm, awarded by the prestigious Malaysian Book of Records in 2016, operated in a certified Current Good Manufacturing Practice (cGMP) laboratory following PIC/S standards by the National Pharmaceutical Regulatory Agency (NPRA), a division of the Ministry of Health Malaysia.

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