ALZHEIMER'S DISEASE

INTRODUCTION

​Alzheimer’s disease : ​Alzheimer’s disease is a neurodegenerative condition that progressively destroys brain cells and causes brain atrophy.

ALZHEIMER'S DISEASE ALZHEIMER'S DISEASE

Memory loss and cognitive impairment are common symptoms of Alzheimer’s disease (AD), a progressive neurological disorder.

The most common form of AD is late-onset, in which individuals are typically diagnosed after the age of 65. However, there is also early-onset Alzheimer’s, which affects individuals under the age of 65 and is typically identified in individuals in their 40s or 50s.


Another type of AD is familial Alzheimer’s disease (FAD), which is caused by inherited genetic mutations. FAD accounts for less than 1% of all AD cases and is often the cause of early-onset AD.

SYMPTOMS

Some of the symptoms experienced by individuals with Alzheimer’s include

  • Memory loss 
  • Difficulty thinking and reasoning 
  • Change in behavior and personality 
  • Struggling with what once was a familiar task
  • Decline in the ability to make decisions and judgments

WHAT CAUSE THE DISEASE? THE DISEASE?

Figure 2 The illustration of how the formation of plaque and tangles result in Alzheimer’s disease.

​The main causes of Alzheimer’s disease are the failure of synapses and the abnormal accumulation of proteins in and around brain cells. Amyloid-beta plaques and neurofibrillary tangles have been identified as significant contributors to the development of the disease, based on brain autopsy studies of Alzheimer’s patients.

CURRENT TREATMENTS TREATMENTS

There are several medications currently available for the treatment of Alzheimer’s disease. However, when a person receives treatment, their symptoms may temporarily improve (usually for a period of between six and 12 months). In the months that follow, symptoms may gradually worsen as the treatment’s effectiveness wears off, even though the person is still taking the medication.

NAME OF DRUGS

COMMON SIDE EFFECTS

Aducanumab

Amyloid-related imaging abnormalities (ARIA), can lead to fluid buildup or bleeding in the brain; also headache, dizziness, falls, diarrhea, confusion.

Donepezil

Nausea, vomiting, diarrhea, muscle cramps, fatigue, weight loss.

Memantine

Dizziness, headache, diarrhea, constipation, confusion.

WHAT WE OFFER? OFFER?

EXOSOME RESEARCH - CELLTIX CELLTIX

CelltiX is a type of extracellular vesicle from Umbilical Cord-Derived Mesenchymal Stem Cells (MSCs) manufactured in a cGMP-compliant facility.

It is a novel form of a major paracrine factor released by MSCs into a culture medium, which plays an important role in a wide range of biological processes.

STEM CELL RESEARCH - CELLTIMAX CELLTIMAX

CelltiMax is a product derived from human umbilical cord-derived Mesenchymal Stem Cells (MSCs). The cells are cultured, then administered to the patient via intramuscular or intravenous injection. They have the ability to differentiate into specialized cells with specific functions for various parts of the body, and can reduce inflammation, repair, renew, regenerate, and replace damaged cells.

BENEFITS OF OUR TREATMENTS? OUR TREATMENTS?

STEM CELL RESEARCH

EXOSOME RESEARCH

Accelerates healing

Reduced inflammation

Eliminates pain and inflammation

Supports metabolic function

Avoids the need for surgery

Improves brain health

Enhances collagen production

Reduces chronic pain

Decrease nerve damage

Enhances tissue regeneration

Less invasive procedure

Boost immune health

HOW IT WORKS? WORKS?

Stem Cell Research (CelltiMax)

  • Replaces the neuronal cells that have been injured or lost.
  • Secretes neurotrophic factors.
  • Anti-amyloid protein production.
  • Have anti-inflammatory activities.
  • Promotes activation of endogenous stem cells.
  • Ameliorate the neuron’s metabolic activity in the brain.

Figure 4 The pathological role of exosomes in Alzheimer

Exosome Research (CelltiX)

  • Exosomes can carry Aβ plaques and tau protein, whose accumulation is responsible for causing Alzheimer.

Figure 3 illustrates the stem cell mechanisms of action to treat Alzheimer’s disease

TALK TO US

If you believe that our treatment options may be able to improve your condition and enhance your quality of life, please contact us to schedule a complimentary consultation with one of our in-house clinical specialists. Our consultations are available in both Malay and English language.

To schedule your consultation, click the button below

​During your consultation, we will: we will:

Review your medical history & recent evaluations

Explore what your treatment package might look like​

Answer any questions you have about us

Answer any questions you have about the therapies

Discuss practical next steps, ​if you feel we can effectively treat you

Review your medical history & recent evaluations

Explore what your treatment package might look like​

Answer any questions you have about us

Answer any questions you have about the therapies

Discuss practical next steps,
​if you feel we can effectively treat you