A telomere is a section of nucleotide sequences that repeat at both ends of a chromosome. It guards the genome against unwanted recombination, repair, or fusion with nearby chromosomes as well as nucleolytic destruction.
Telomere shortening, which is widely recognized as a symptom of aging and to which even stem cells are susceptible, has attracted a lot of interest especially in age-related illnesses. In actuality, accelerated telomere shortening is the root cause of many aging-related disorders, including higher cancer risk, coronary heart disease, heart failure, diabetes, and osteoporosis. The cell changes when telomeres are critically shortened. Senescent cells stop dividing and may experience apoptosis.