VAGINAL REJUVENATION

INTRODUCTION

Vaginal rejuvenation : Is a broad term for vaginal corrective treatments. These procedures can be done for cosmetic reasons or to solve age-related problems, such as lack of vaginal tightness and urinary incontinence

VAGINAL REJUVENTION

Vaginal rejuvenation is a broad term that refers to a variety of vaginal rejuvenation procedures. Your vagina and surrounding tissues may lose elasticity and strength due to factors ranging from childbirth to ageing to genetics. This causes incontinence (leaking urine), vaginal dryness, sagging skin, and a lack of sexual pleasure.

Many women and people who were Assigned Female At Birth (AFAB) seek vaginal rejuvenation to improve these conditions and restore the appearance and function of their vagina. Vaginal rejuvenation can be accomplished surgically or nonsurgical.

WHY DO PEOPLE GET VAGINAL REJUVENTION? VAGINAL REJUVENTION?

Illustration of Vagina before and after get Varginal Rejuvention.

People get vaginal rejuvenation to address common issues associated with having children or menopause, including vaginal looseness, lack of lubrication and loss of sexual intimacy. Treatment can help minimize these symptoms as well as:

- Loose skin around the vagina
- Leaking urine when jumping, sneezing, or laughing
- Not being able to hold your urine
- Decreased libido
- Excess dryness
- Painful sex
- Loss of sensation and sexual satisfaction
- Lack of confidence or low self-esteem

SYMTOMPS

DISEASE

SYMTOPMS

Vaginal Laxity

To tighten the vagina at the introitus and the full length of the vaginal canal.

Vulvar/Labial Laxity

To tighten the labial tissues and reduce noticeable sag.

Vaginal/Vulvar Dryness or Atrophic Vaginitis

To add softer and thicker skin and relieve dryness without the use of hormones.

Mild to Moderate Stress Incontinence

To reduce accidents and leakage, and possibly reduce urge symptoms. Used with consistent Kegel exercises, ThermiVa may reduce or eliminate the need for mesh slings.

Mild to Moderate Stress Incontinence

To increase sensitivity and strengthen muscular contractions, leading to greater sexual satisfaction for women and their partners.

WHAT CAUSES VAGINAL CHANGE? VAGINAL CHANGE?

Illustration of Pelvic floor trauma because of Child Birth.

There are several big factors that can cause changes in a woman’s vaginal tissue. The two main causes are childbirth and menopause.

Childbirth
There is so much that happens during childbirth that there isn’t just one factor that causes vaginal changes. First, the cervix (the passage at the bottom of the uterus) must dilate by 10 centimetres. When the cervix dilates, the baby can be pushed through the vaginal canal.

Muscles on the pelvic floor push the baby along as it travels. These muscles can sometimes stretch to three times their normal size. Once the baby reaches the vaginal opening, the tissue will stretch as far as it can, but occasionally it will need to stretch beyond its limit, in which case the doctor will form an episiotomy.An episiotomy involves cutting the tissue from the opening of the vagina to the perineum to prevent the skin from ripping.

Menopause

Menopause is another major life event that has a significant impact on the vagina and vaginal tissues. Hormone deficiency causes vaginal walls to thin and become lax or atrophied. As the pelvic floor muscles weaken, the body stops producing natural lubrication, and stress incontinence worsens.

CURRENT TREATMENTS TREATMENTS

Vaginal rejuvenation procedures can be surgical or non-surgical. Treatment affects the vulva (the outer part of the female genitals) and the vaginal canal (where penetration occurs during sex or where you put a tampon).

Surgical methods of vaginal rejuvenation

Surgical methods of vaginal rejuvenation typically involve sedation or anesthesia. A gynecologic or plastic surgeon performs these procedures.

Surgical Procedure

Details

Labiaplasty

Reshaping your labia or the “lips” of your vagina

Vaginoplasty

Tightens or repairs the vaginal canal after childbirth

Clitoral Hood Reduction

Removes extra tissue that covers the clitoris

Monsplasty

Removes fatty tissue from the public bone area

Vulvoplasty

Reshapes the vulvar area (external genitalia)

Perineoplasty

Strengthens the perineum (space between your vaginal and anus)

Nonsurgical methods of vaginal rejuvenation

Nonsurgical methods of vaginal rejuvenation are noninvasive with a short recovery time. They help tighten and tone your vaginal area without needles or surgery. Nonsurgical vaginal rejuvenation involves heating the top layers of vaginal tissue. This causes the underlying tissue to create extra collagen and new, firmer tissue.

Nonsurgical treatment

Details

CO2 Laser treatment

The laser heats the upper layers of the tissue in your vagina, causing the tissue in the lower layers to make more collagen. This makes the skin firmer and tighter. Brand names of laser devices include MonaLisa Touch®, FemTouch® and FemiLift®.

RF (radio frequency) treatment

RF treatment uses electromagnetic waves, similar to the waves used in a microwave (but to a lesser extent). RF waves heat the vaginal tissue, encouraging blood flow and collagen production. Brand names of RF devices include Viveve®, Emsella® and ThermiVA®.

WHAT WE OFFER? OFFER?

EXOSOME RESEARCH - CELLTIX CELLTIX

CelltiX is a type of extracellular vesicle from Umbilical Cord-Derived Mesenchymal Stem Cells (MSCs) manufactured in a cGMP-compliant facility.

It is a novel form of a major paracrine factor released by MSCs into a culture medium, which plays an important role in a wide range of biological processes.

STEM CELL RESEARCH - CELLTIMAX CELLTIMAX

CelltiMax is a product derived from human umbilical cord-derived Mesenchymal Stem Cells (MSCs). The cells are cultured, then administered to the patient via intramuscular or intravenous injection. They have the ability to differentiate into specialized cells with specific functions for various parts of the body, and can reduce inflammation, repair, renew, regenerate, and replace damaged cells.

COMPARISON BETWEEN STEM CELLS AND EXOSOMES AND EXOSOMES

CRITERIAS

STEM CELLS

EXOSOME

Definition

Stem cells are unspecialized cells of the human body.

Extracellular vesicles, which is the medical term for tiny bubbles that are released from stem cells.

Function

Unique, can become any type of cell, and they act as both building blocks and repair mechanisms in your body.

Carry genetic information and proteins to cells throughout your body, and they create paths for communication between cells.

Origins

Donor stem cells are placed in your body and are guided into becoming specific cells in the body to replace and repair diseased cells.

Exosomes are extracted from donated human mesenchymal stem cells (MSCs) and sterilized.

Growth Factors

Less amount of growth factors compared to exosomes.

Exosomes contain nearly three times the amount of growth factors. More growth factors mean a better ability to restore and revitalize target cells.

Administration

- IV Stem Cell Research (Intravenous administration)
- Intrathecal (directly into the spinal canal)
- Site injections into problem areas (Knee, hips, hands, etc)

- Intravenous (IV) research
- Direct injection in the treatment area

BENEFITS OF OUR TREATMENTS? OUR TREATMENTS?

STEM CELL RESEARCH

EXOSOME RESEARCH

Improve bodies’ natural healing abilities

High stabililty

Modulate the immune system

Low toxicity and immunogenicity

Locate and reduce areas of inflammation

High penetration

Replace damaged and diseased cells

Enhanced delivery efficiency

HOW IT WORKS? WORKS?

The Mesenchymal stem cell-based bioengineered constructs enhance vaginal repair.

Histological and biochemical analyses revealed that the content of collagen I, elastin, and microvascular density in the lamina propria of the vagina increased significantly in the MSC group compared to the saline group 12 weeks after MSC transplantation. In addition, the fraction of smooth muscle in the vaginal muscularis increased significantly in the MSC group. MSC transplantation also improved the biomechanical properties of the vagina by increasing the elastic modulus.

Vaginal MSC transplantation has the potential to repair weak vaginal tissue by promoting extracellular matrix ingrowth, neovascularization, and smooth muscle formation, as well as improve the biomechanical properties of the vagina, providing a new treatment option.

TALK TO US

If you feel we might be able to offer meaningful improvement to both your condition and your quality of life, then please reach out to schedule a free consultation with one of our in-house clinical experts. We offer consultations in both Malay and English.

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During your consultation, we will: we will:

Review your medical history & recent evaluations

Explore what your treatment package might look like

Answer any questions you have about us

Answer any questions you have about the therapies

Discuss practical next steps,
if you feel we can effectively treat you