ACUTE/CHRONIC KIDNEY DISEASE

INTRODUCTION

Chronic renal disease, usually referred to as CKD or chronic kidney disease, is a disorder in which kidney function gradually declines over time while Acute Kidney Disease which is referred as AKD is a rapid decrease in renal function over days to weeks.

ACUTE/CHRONIC KIDNEY DISEASE

Acute/chronic kidney disease (A/CKD), commonly known as kidney failure or renal failure, is a medical disorder where the kidneys lose some of their capacity to filter waste materials and extra fluid from the bloodstream. The accumulation of waste materials and fluids in the body can have a negative impact on other body systems and our health. 

The reason the condition is referred to as “chronic” is because the kidneys’ damage develops gradually over a lengthy period of time. Besides, Acute Kidney Disease refers to a sudden episode of kidney failure or kidney damage that happens within a few hours or a few days. 

STAGES OF KIDNEY DISEASES KIDNEY DISEASES

Stages of kidney disease.

SYMPTOMS

People with A/CKD may not feel ill or notice any symptoms. The only way to find out is through specific blood and urine tests. These tests include the measurement of both the creatinine level in the blood and protein in the urine.

As kidney disease gets worse, a person may have swelling, called edema. Edema happens when the kidneys can’t get rid of extra fluid and salt. Edema can occur in the legs, feet, or ankles, and less often in the hands or face.

Other symptoms of advanced A/CKD are chest pain, itching or numbness, muscle cramps, nausea, weight loss, sleep problems, shortness of breath, headaches, increased or decreased urination, and blood in the urine.

WHAT CAUSES THE DISEASE? THE DISEASE?

Causes of chronic kidney disease.

Diabetes, hypertension, cardiovascular diseases (CVD), and cigarette smoking are the common risk factors of chronic kidney disease (CKD).

​The common causes of acute kidney failure include:

    • Autoimmune kidney diseases
    • Certain medications
      Severe dehydration
    • A urinary tract obstruction
    • Untreated systemic diseases, such as heart or liver disease

CURRENT TREATMENT TREATMENT

The treatment of acute/chronic kidney disease will depend on the stage of the kidney disease. There are several main treatments which are

1. Medicine
There’s no medicine specifically for acute/chronic kidney disease, but medicine can help control many of the problems that cause the condition and the complications that can happen as a result of it.

CAUSES

NAME OF MEDICINE

High blood pressure

​Angiotensin Converting Enzyme (ACE)

High cholesterol

Statins

High potassium

Sodium Zirconium Cyclosilicate

Anaemia

Iron

Bone problems

Calcium acetate
​Calcium carbonate

2. Dialysis
This is a method of removing waste products and excess fluid from the blood. However, dialysis is not regarded as the best course of treatment due to the high expenses of care and detrimental effects on the patient’s quality of life 

  • Haemodialysis – this involves diverting blood into an external machine, where it’s filtered before being returned to the body
  • Peritoneal dialysis – this involves pumping dialysis fluid into a space inside your tummy to draw out waste products from the blood as they pass through vessels lining the inside of your tummy

 3. Kidney transplant
An alternative to dialysis for people with severely reduced kidney function is a kidney transplant. This is often the most effective treatment for advanced kidney disease, but it involves major surgery and taking medicines (immunosuppressants) to stop the body attacking the donor organ. Besides, its usage is restricted because to the severe lack of organ donors and the possibility of organ rejection.

WHAT WE OFFER? OFFER?

EXOSOME RESEARCH - CELLTIX CELLTIX

CelltiX is a type of extracellular vesicle from Umbilical Cord-Derived Mesenchymal Stem Cells (MSCs) manufactured in a cGMP-compliant facility.

It is a novel form of a major paracrine factor released by MSCs into a culture medium, which plays an important role in a wide range of biological processes.

STEM CELL RESEARCH - CELLTIMAX CELLTIMAX

CelltiMax is a product derived from human umbilical cord-derived Mesenchymal Stem Cells (MSCs). The cells are cultured, then administered to the patient via intramuscular or intravenous injection. They have the ability to differentiate into specialized cells with specific functions for various parts of the body, and can reduce inflammation, repair, renew, regenerate, and replace damaged cells.

BENEFITS OF OUR TREATMENTS OUR TREATMENTS

STEM CELL RESEARCH

EXOSOME RESEARCH

Accelerates healing

Reduced inflammation

Eliminates pain and inflammation

Supports metabolic function

Avoids the need for surgery

Improve brain health

Enhances collagen production

Reduces chronic pain

Decrease nerve damage

Enhances tissue regeneration

Less invasive procedure

Boost immune health

HOW IT WORKS? WORKS?

mscs-1-1_orig

Mechanism of Mesenchymal stem cells to kidney.

Acute Kidney Disease

    • Promote effective regenerative processes
    • Decreasing tubular injury
    • Promoting angiogenesis
    • Reducing oxidative stress
    • Reducing inflammation
    • Promoting a pro-regulatory and anti-inflammatory phenotype

Chronic Kidney Disease

    • Promoting renal regeneration
    • Reducing renal levels of oxidative stress
    • Reducing renal levels of apoptosis
    • Reducing renal levels of fibrosis

TALK TO US

​If you feel we might be able to offer meaningful improvement to both your condition and your quality of life, then please reach out to schedule a free consultation with one of our in-house clinical experts. We offer consultations in both Malay and English. 

To schedule your consultation, click the button below

​During your consultation, we will: we will:

Review your medical history & recent evaluations

Explore what your treatment package might look like​

Answer any questions you have about us

Answer any questions you have about the therapies

Discuss practical next steps, ​if you feel we can effectively treat you

Review your medical history & recent evaluations

Explore what your treatment package might look like​

Answer any questions you have about us

Answer any questions you have about the therapies

Discuss practical next steps,
​if you feel we can effectively treat you